The episode starts with Timmy complaining about having to clean the garage when an angry Chloe walks in and both yell "WORST DAY EVER!". Chloe rants about being chosen for participation in a Hamburger eating contest for Charity and she can't since she is a vegetarian and hates meat while Timmy says he loves meat but hates organizing, which is something Chloe adores. Cosmo then gives them the idea of wishing they switch bodies so that they can do the activity that once loves but the other hates and Cosmo grants their wish. Timmy in Chloe's body, marvels over the fact that he is pretty and can eat hamburgers and Chloe marvels at the fact that she now has Timmy's big teeth and can spend the entire Sunday organizing while Cosmo claims his mind is blown as he is confused about how Timmy and Chloe are in each other's bodies but kept their original voices.
Timmy/Chloe wins 1st place at the contest and wins a trophy full of hamburgers as well as winning the burping contest while Chloe/Timmy is happily organizing the Turner's garage, which impresses Timmy's dad. However, when they reunite in Timmy's bedroom, Chloe is horrified at the fact that Timmy turned her body into a "toxic dump" and demands they switch back but unfortunately Cosmo and Wanda are unable to do so since Cosmo accidentally threw their wands in the garbage the first time his mind was blown so Wanda tells the kids to wait this out until she and Cosmo can find their wands while she searches for their wands in the garbage so the kids have no choice but to pretend to be each other.
At the Charmicael's house, Chloe's mother announces dinner is ready and Timmy/Chloe goes to Chloe's house, where Chloe's mother tells "her daughter" that she made her (Chloe's) favorite food: mock cheese and kelp casserole, which repulses Timmy/Chloe so he decides to keep eating the burgers from his trophy, much to the shock of Chloe's parents, which disgusts Chloe's parents as they are also vegetarians.
At the Turner residence, Timmy's mother asks Chloe/Timmy to set the table but when she opens a cabinet Timmy's father's scary puppets fall on her so Chloe/Timmy opens another cabinet and see Timmy's mother's medieval's fighting equipment so she asks them to remind "him" where do they keep their dishes and utensils but when Timmy's parents tell her that they hide them like Easter Eggs Chloe/Timmy snaps, searches for all the utensils, places them in their proper place while labeling them and angrily tells Timmy's parents to be quiet since "he" is organizing. When Timmy's mother assumes her son is irritated because he is hungry she offers to get their dinner out of the laundry hamper, which makes Chloe/Timmy angrier and shoots labels that say "weirdo" at them.
At night, Chloe complains about his house and how hard it is to floss Timmy's teeth but Timmy tells her to calm down since he is sure that Wanda will find the wands soon right before Wanda gets accidentally taken by the garbage truck. Suddenly, someone knocks on Chloe's closet door and Chloe tells Timmy she has a vicious man eating plant there that he needs to feed ten minutes every night, the plant breaks out of the closet while a robot comes out of Timmy's closet and challenges Chloe to fight and Timmy warns her that he uses the robot to keep his fighting skills sharp.
The following day, the Carmichaels and the Turners have a sit down at the Turner residence, where the parents tell each other about their kids' "crazy" behavior and blame each other's child for it. Timmy/Chloe tries to reassure Chloe's parents that she is the same old Chloe but then he burps and says he is failing math, which causes Clark to faint and Chloe's mother to scold Timmy/Chloe. Timmy's mother then claims that the only solution is to separate their children, which Chloe's mother agrees to and reveals that she and Clark are taking Chloe and moving away as soon as Clark regains consciousness. Timmy's father agrees and tells them to leave while Timmy and Chloe exchange sad looks before he leaves. Later in Timmy's treehouse, the kids come up with a plan to stop Chloe's family from moving away: Chloe in Timmy's body dresses in her normal clothes with a blonde wig while Timmy in Chloe's body also dresses in his own clothes, covers his hair in a hair net and uses fake buck teeth, which again blows Cosmo's mind.
At the Carmichael residence, Chloe manages to convince her parents that her behavior was the result of a "brief rebellious phase", brought up her math grade to an "A+ infinity" and eats kelp casserole, much to the delight of her parents. Chloe's mother changes her mind about moving away while her father faints after drinking chocolate milk to celebrate. At the Turner residence Timmy asks his parents for some "laundry hamper casserole" and burps, much to his parents' joy.