When Cosmo was a woman, his name was Cosma. Therefore, for a short period of time, his name was Cosma Cosma.
Trixie is secretly revealed to be a tomboy who likes boys' comics and video games. However, this character trait is never elaborated beyond this episode, although it's possible that this side of her personality is hinted in "The Big Superhero Wish!" and "Wishology." In both specials, she enjoys being in action scenes.
The title card features items girls would want (such as a pearl necklace and a diamond ring), though Timantha used or liked none of these.
When Timmy turned into Timantha and looked into the mirror, he shrieks like a girl, similar to his father.
This episode was ranked #33 in the 100 Greatest Nicktoon Episodes countdown.
Timmy and his friends have failed to get into birthday parties that Trixie had in the past (as hinted by Chester).
At the end of the episode, Cosmo's birth nose made him look like his brother Schnozmo.
Timmy is revealed to not like dead frogs regardless of what gender he is, while Trixie does.
This episode's moral was that it's okay for girls to like boy things and vice versa.
Trixie in her tomboyish side will be briefly seen again in Season 9's "Finding Emo" but, somehow with different colored clothes and hair.
This episode was included on Volume 1 of The Fairly OddParents for Game Boy Advance Video.
This episode and "Foul Balled" premiered on the same day Disney's Kim Possible premiered.
Chester: Dude, boys like comic books; girls like dolls. Boys like video games; girls like makeup. We're different! That's why we have different bathrooms!
Veronica: [comes out of stall] Um, am I in the wrong room?
Chester: [screams and then starts tearing away at the boards on the door] Nothing makes sense anymore!!
A.J.: [to Veronica] Frog?
Trixie: You know, all week, people have been asking me what I wanted for my birthday, and you've given it to me.
Timantha: I have?
Trixie: You've given me a friend who likes me for whom I am.
Timantha: That's all you wanted for your birthday? A friend?
Trixie: Yep! Someone who isn't afraid to say "Hey, I like Kissy Kissy Goo Goo and Skull Squisher!" If you were a boy, I'd totally date you.
Timmy: Trixie! *Ahem* [inter-spliced with "blah-blahs"] You know, I like you for who you are... [Trixie gets out a translator] ...not for what everyone expects you to be; a friend to you, someone who isn't afraid to say, 'Hey, I like Kissy Kissy Goo Goo and Skull Squisher too!'
Trixie: Oh my gosh! That is so sweet... but, uhh, that's what I have girlfriends for. SECURITY!
Cosma\Cosmo: What do think? This? Or this? Which goes better with my eyes?
Wando\Wanda: Just pick something!
Cosma\Cosmo: Oh, I give up! [flies into bathroom] [SPlASH] Would it kill you to leave the lid down?
Wando\Wanda: Would it kill you to look before you sit? [belches]
Timmy: I wish you were back to the way you were born! [Cosmo and Wanda grant the wish and return to how they were born]
Cosmo: [appears with a big nose] What? This was the nose I was born with! Can't a guy do something to make himself look pretty?
Elmer: Timmy sir, are you watching one of those dumb girly soap operas?